Rebuilding Neural Pathways Through Advanced Lipid Science…

Dr. Siobhan Newman shares insights from her clinical experience with plasmalogen therapy and its remarkable impact on cognitive health. Drawing from 30+ years of Emergency Department experience and her recent role as Medical Director working alongside pioneering biochemist Dr. Dayan Goodenowe of Prodrome Science, she reveals how this innovative approach is transforming our understanding of neurodegeneration.

In this article:

• Understanding Plasmalogens and Neural Health
• The Science Behind Myelin Regeneration
• Clinical Success Stories in Cognitive Enhancement
• Prevention and Treatment Protocols

My journey into plasmalogen therapy began with a profound understanding: traditional approaches to cognitive decline weren’t addressing the fundamental cellular mechanisms of neural degeneration. As an emergency physician, I’ve witnessed the devastating progression of neurodegenerative conditions, often feeling limited in our ability to offer truly transformative solutions. That changed when I discovered the groundbreaking work in plasmalogen science.

Plasmalogens are specialized phospholipids that play a crucial role in cellular membrane structure and function, particularly in neural tissue. What makes them extraordinary is their ability to rebuild the myelin walls of neural axons – essentially reconstructing the communication pathways in our brain. This isn’t just theory; we’re seeing remarkable results in clinical practice, supported by extensive research demonstrating their role in inhibiting neuroinflammation and promoting cognitive function.

A recent case exemplifies the potential of this therapy. My 93-year-old patient presented with significant cognitive impairment. After implementing our specialized plasmalogen protocol, we observed remarkable improvements in cognitive function within just one month. Her vital signs stabilized at impressive levels – blood pressure 138/85, pulse 72, and oxygen saturation 96% – but more significantly, her mental acuity showed dramatic enhancement. Here is a quote from her physical therapist, who is unaware of the details of my protocol:

“Hey Dr. Newman, your patient’s vitals are amazing…. Whatever new protocol you got her on is working. She’s much sharper than she was like even a month ago.” -Saro, PT and Owner of Homehealth

The Science Behind the Success:

Plasmalogens work differently from traditional omega-3 and omega-9 supplements. While these essential fatty acids are important, their bioavailability is often compromised by digestive processes. Current research has revealed that plasmalogens act as precursor molecules that survive the digestive tract and serve as cellular manufacturing plants, producing the crucial lipids needed for neural repair. Studies have shown they can effectively inhibit neuroinflammation while promoting healthy cognitive function through multiple pathways.

This approach is showing promise across a spectrum of conditions:

• Alzheimer’s Disease
• General Dementia
• Multiple Sclerosis
• ALS
• Autism Spectrum Disorders
• Traumatic Brain Injury

What sets plasmalogen therapy apart is its ability to not just halt decline but potentially reverse it. Through advanced diagnostic imaging, we’re seeing something previously thought impossible: increases in brain volume among treated patients. Recent studies have demonstrated that plasmalogens can effectively inhibit neuroinflammation and enhance memory function through specific cellular signaling pathways.

Prevention and Treatment:

While lifestyle factors and diet remain foundational to brain health, once neurodegenerative conditions manifest, rebuilding neural architecture becomes crucial. My protocol focuses on:

• Precise dosing of bioavailable plasmalogen compounds
• Gut-health support and key cellular nutrients
• BHRT and Peptides when appropriate
• Customized treatment schedules
• Regular monitoring of cognitive function
• Integration with existing health protocols

The Future of Neurological Health:

Working alongside Dr. Goodenowe and his team, we’re continuing to advance our understanding of these remarkable compounds. New diagnostics being developed promise to revolutionize how we assess and treat neurological conditions, potentially offering early intervention opportunities before significant decline occurs.

Maybe it’s time to Rethink Aging and cognitive health through the lens of cellular membrane science.

Did you know?

Plasmalogens make up approximately 20% of the total phospholipid mass in humans? Their levels naturally decline with age, but through targeted supplementation, we can now address this crucial aspect of brain health.

References

Su, X. Q., et al. (2019). Plasmalogens and Alzheimer’s disease: A review. Lipids in Health and Disease, 18(1), 100. https://doi.org/10.1186/s12944-019-1044-1

Hossain, M. S., et al. (2023). Plasmalogens inhibit neuroinflammation and promote cognitive function. Brain Research Bulletin, 192, 56-61.

Goodenowe, D. B., et al. (2007). Peripheral ethanolamine plasmalogen deficiency: A logical causative factor in Alzheimer’s disease and dementia. Journal of Lipid Research, 48(11), 2485-2498.

Fujino, T., et al. (2020). Efficacy and blood plasmalogen changes by oral administration of plasmalogen in patients with mild Alzheimer’s disease and mild cognitive impairment: A multicenter, randomized, double-blind, placebo-controlled trial. EBioMedicine, 17, 199-205.